Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates

Linder, David; Austeri, Martina; Lacour, Jérôme

doi:10.1039/b910475e

Scientific article

English

Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates

ContributorsLinder, David; Austeri, Martina; Lacour, Jérôme

Published inOrganic & biomolecular chemistry, vol. 7, no. 19, p. 4057-4061

Publication date2009

Abstract

The addition of a Lewis acidic metal triflate salt Mg(OTf)(2) as co-catalyst in the CpRu-catalyzed decarboxylative allylation of in situ-generated ketone enolates allows the reaction to proceed at lower temperature with higher regio- and enantioselectivity. Even so-far-unreactive substrates react.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

LINDER, David, AUSTERI, Martina, LACOUR, Jérôme. Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates. In: Organic & biomolecular chemistry, 2009, vol. 7, n° 19, p. 4057–4061. doi: 10.1039/b910475e

Article

Identifiers

PID : unige:7960
DOI : 10.1039/b910475e
PMID : 19763311

Journal ISSN1477-0520

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Lewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates

The addition of a Lewis acidic metal triflate salt Mg(OTf)(2) as co-catalyst in the CpRu-catalyzed decarboxylative allylation of in situ-generated ketone enolates allows the reaction to proceed at lower temperature with higher regio- and enantioselectivity. Even so-far-unreactive substrates react.

Technical informations