γHV68 vGAT: a viral pseudoenzyme pimping for PAMPs

Kolakofsky, Daniel; Garcin, Dominique

doi:10.1016/j.molcel.2015.03.021

Scientific article

Open access

English

γHV68 vGAT: a viral pseudoenzyme pimping for PAMPs

ContributorsKolakofsky, Daniel; Garcin, Dominique

Published inMolecular cell, vol. 58, no. 1, p. 3-4

Publication date2015

Abstract

In this issue, He et al. (2015) show how herpes virus usurps a cellular metabolic enzyme to induce RIG-I deamidation and RNA-independent activation, likely to better prevent further innate immune responses.

Keywords

Animals
Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor/immunology
DEAD-box RNA Helicases/immunology
Gammaherpesvirinae/immunology
Humans
Immune Evasion/genetics
RNA, Viral/immunology
Viral Proteins/immunology

Affiliation

Faculté de médecine / Section de médecine fondamentale / Département de microbiologie et médecine moléculaire

Citation (ISO format)

KOLAKOFSKY, Daniel, GARCIN, Dominique. γHV68 vGAT: a viral pseudoenzyme pimping for PAMPs. In: Molecular cell, 2015, vol. 58, n° 1, p. 3–4. doi: 10.1016/j.molcel.2015.03.021

Article (Published version)

Identifiers

PID : unige:79565
DOI : 10.1016/j.molcel.2015.03.021
PMID : 25839430

ISSN of the journal1097-2765

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Creation10/22/2015 4:01:00 PM

First validation10/22/2015 4:01:00 PM

Update time03/15/2023 12:03:49 AM

Status update03/15/2023 12:03:49 AM

Last indexation01/16/2024 8:01:43 PM

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γHV68 vGAT: a viral pseudoenzyme pimping for PAMPs

In this issue, He et al. (2015) show how herpes virus usurps a cellular metabolic enzyme to induce RIG-I deamidation and RNA-independent activation, likely to better prevent further innate immune responses.

Technical informations