Scientific article

A review of multisite pacing to achieve cardiac resynchronization therapy

Published inEuropace, vol. 17, no. 1, p. 7-17
Publication date2015

Non-response to cardiac resynchronization therapy remains a significant problem in up to 30% of patients. Multisite stimulation has emerged as a way of potentially overcoming non-response. This may be achieved by the use of multiple leads placed within the coronary sinus and its tributaries (dual-vein pacing) or more recently by the use of multipolar (quadripolar) left ventricular pacing leads which can deliver pacing stimuli at multiple sites within the same vein. This review covers the role of multisite pacing including the interaction with the underlying pathophysiology, the current and planned studies, and the potential pitfalls of this technology.

  • Animals
  • Bundle-Branch Block/complications/prevention & control
  • Cardiac Resynchronization Therapy/adverse effects/methods
  • Evidence-Based Medicine
  • Heart Failure/complications/prevention & control
  • Humans
  • Patient Selection
  • Treatment Outcome
  • Ventricular Fibrillation/etiology/prevention & control
Citation (ISO format)
RINALDI, Christopher Aldo et al. A review of multisite pacing to achieve cardiac resynchronization therapy. In: Europace, 2015, vol. 17, n° 1, p. 7–17. doi: 10.1093/europace/euu197
Main files (1)
Article (Published version)
ISSN of the journal1099-5129

Technical informations

Creation10/14/2015 9:46:00 PM
First validation10/14/2015 9:46:00 PM
Update time03/15/2023 12:03:14 AM
Status update03/15/2023 12:03:13 AM
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