UNIGE document Scientific Article
previous document  unige:7917  next document
add to browser collection

Synthetic peroxides as antimalarials

Published in Current Opinion in Investigational Drugs. 2004, vol. 5, no. 8, p. 866-872
Abstract This review describes the present status of purely synthetic peroxides and 1,2,4-trioxanes and how they perform in various preclinical tests as potential antimalarial drug candidates. The literature is reviewed from 1986 onwards, comprising mostly articles published in the last ten years. As several papers on antimalarial peroxides have already been published, this review focuses on more recent studies detailing the novelty and potential of synthetic peroxides.
Keywords ArtefleneBridged bicyclic peroxidesChimerical molecules1,2-dioxanesFormulationIn vitro activityIn vivo activityPlasmodiumResistance1,2,4,5-tetraoxanesToxicity1,2,4-trioxanes
Full text
Article (Published version) - document accessible for UNIGE members only Limited access to UNIGE
(ISO format)
JEFFORD, Charles. Synthetic peroxides as antimalarials. In: Current Opinion in Investigational Drugs, 2004, vol. 5, n° 8, p. 866-872. doi: 10.1002/med.10066 https://archive-ouverte.unige.ch/unige:7917

453 hits



Deposited on : 2010-06-21

Export document
Format :
Citation style :