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Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment

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Published in Depression and Anxiety. 2016, vol. 33, no. 1, p. 45-55
Abstract Serotonin 3A receptor (5-HT3A R) is associated at the genetic and epigenetic levels with a variety of psychiatric disorders and interacts with early-life stress such as childhood maltreatment. We studied the impact of childhood maltreatment on the methylation status of the 5-HT3A R and its association with clinical severity outcomes in relation with a functional genetic polymorphism.
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PMID: 26350166
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Structures
Research groups Thérapeutiques des Troubles de l'Humeur et Anxieux (689)
Groupe Dayer Alexandre (Formation du circuit cortical) (875)
Groupe Giacobino Ariane (génétique) (923)
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PERROUD, Nader Ali et al. Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment. In: Depression and Anxiety, 2016, vol. 33, n° 1, p. 45-55. https://archive-ouverte.unige.ch/unige:78757

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Deposited on : 2015-12-17

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