Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

Quteineh, Lina; Vandenberghe, Frederik; Saigi Morgui, Nuria; Delacrétaz, Aurélie; Choong, Eva; Gholam-Rezaee, Mehdi; Magistretti, Pierre; Bondolfi, Guido; Von Gunten, Armin; Preisig, Martin; Castelao, Enrique; Vollenweider, Peter; Waeber, Gerard; Bochud, Murielle; Kutalik, Zoltán; Conus, Philippe; Eap, Chin Bin

doi:10.1097/FPC.0000000000000131

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Title		Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments
Authors		Quteineh, Lina Vandenberghe, Frederik Saigi Morgui, Nuria Delacrétaz, Aurélie Choong, Eva Gholam-Rezaee, Mehdi Magistretti, Pierre Bondolfi, Guido Von Gunten, Armin Preisig, Martin Castelao, Enrique Vollenweider, Peter Waeber, Gerard Bochud, Murielle Kutalik, Zoltán Conus, Philippe Eap, Chin Bin show all authors [1 - 17]
Published in		Pharmacogenetics and genomics. 2015, vol. 25, no. 5, p. 246-258
Abstract		Metabolic syndrome (MetS) associated with psychiatric disorders and psychotropic treatments represents a major health issue. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an enzyme that catalyzes tissue regeneration of active cortisol from cortisone. Elevated enzymatic activity of 11β-HSD1 may lead to the development of MetS.
Identifiers		DOI: 10.1097/FPC.0000000000000131 PMID: 25751397
Full text		Article (Published version) (162 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté des sciences / Section des sciences pharmaceutiques
Research group		Médecine psychosomatique, neurosciences cliniques et mindfulness (690)
Citation (ISO format)		QUTEINEH, Lina et al. Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments. In: Pharmacogenetics and genomics, 2015, vol. 25, n° 5, p. 246-258. doi: 10.1097/FPC.0000000000000131 https://archive-ouverte.unige.ch/unige:78753