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Qualitative and Quantitative Evaluation of Blob-Based Time-of-Flight PET Image Reconstruction in Hybrid Brain PET/MR Imaging

Published inMolecular imaging and biology, vol. 17, no. 5, p. 704-713
Publication date2015
Abstract

Many neurological diseases affect small structures in the brain and, as such, reliable visual evaluation and accurate quantification are required. Recent technological developments made the clinical use of hybrid positron emission tomography/magnetic resonance (PET/MR) systems possible, providing both functional and anatomical information in a single imaging session. Nevertheless, there is a trade-off between spatial resolution and image quality (contrast and noise), which is dictated mainly by the chosen acquisition and reconstruction protocols. Image reconstruction algorithms using spherical symmetric basis functions (blobs) for image representation have a number of additional parameters that impact both the qualitative and quantitative image characteristics. Hence, a detailed investigation of the blob-based reconstruction characteristics using different parameters is needed to achieve optimal reconstruction results.

Citation (ISO format)
LEEMANS, Eva L et al. Qualitative and Quantitative Evaluation of Blob-Based Time-of-Flight PET Image Reconstruction in Hybrid Brain PET/MR Imaging. In: Molecular imaging and biology, 2015, vol. 17, n° 5, p. 704–713. doi: 10.1007/s11307-015-0824-x
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ISSN of the journal1536-1632
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Creation12/03/2015 2:37:00 PM
First validation12/03/2015 2:37:00 PM
Update time03/14/2023 11:59:15 PM
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