Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up

Schoindre, Yoland; Jallouli, Moez; Tanguy, Marie-Laure; Ghillani, Pascale; Galicier, Lionel; Aumaître, Olivier; Francès, Camille; Le Guern, Véronique; Lioté, Frédéric; Smail, Amar; Limal, Nicolas; Perard, Laurent; Desmurs-Clavel, Hélène; Le Thi Huong, Du; Asli, Bouchra; Kahn, Jean-Emmanuel; Sailler, Laurent; Ackermann, Félix; Papo, Thomas; Sacré, Karim; Fain, Olivier; Stirnemann, Jérôme; Cacoub, Patrice; Leroux, Gaëlle; Cohen-Bittan, Judith; Hulot, Jean-Sébastien; Lechat, Philippe; Musset, Lucile; Piette, Jean-Charles; Amoura, Zahir; Souberbielle, Jean-Claude; Costedoat-Chalumeau, Nathalie

doi:10.1136/lupus-2014-000027

Scientific article

Open access

English

Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up

Published inLupus science & medicine, vol. 1, no. 1, e000027

Publication date2014

Abstract

Growing evidence suggests that vitamin D plays a key role in the pathogenesis and progression of autoimmune diseases, including systemic lupus erythematosus (SLE). Recent studies have found an association between lower serum 25-hydroxyvitamin D (25(OH)D) levels and higher SLE activity. We studied the relationship between 25(OH)D levels and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score, and we assessed for the first time the role of vitamin D in predicting SLE flare-ups.

Affiliation

Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

Research group

Groupe Perrier Arnaud (Médecine interne générale, de réhabilitation et de gériatrie) (585)

Citation (ISO format)

SCHOINDRE, Yoland et al. Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up. In: Lupus science & medicine, 2014, vol. 1, n° 1, p. e000027. doi: 10.1136/lupus-2014-000027

Article (Published version)

Identifiers

PID : unige:78660
DOI : 10.1136/lupus-2014-000027
PMID : 25379192

ISSN of the journal2053-8790

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Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up

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