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Syndrome des antisynthétases : diagnostic et traitements

Published in Revue médicale suisse. 2015, vol. 11, no. 469, p. 808-812
Abstract The anti-synthetases syndrome is a rare disease with a specific constellation of clinical symptoms present in a subset of patients with inflammatory myopathy. Besides constitutional symptoms and myositis, it is associated with mechanic's hands, Raynaud phenomenon, and non-erosive arthritis. This syndrome is characterized by the presence of one of eight auto-antibodies to aminoacyl-transfer ribonucleic acid synthetase enzymes in the serum. Interstitial lung disease is more frequent in this subpopulation of inflammatory myopathy and worsens the patient's prognosis.
Keywords AdultAutoantibodies/immunologyHumansLung Diseases, Interstitial/epidemiology/etiologyMaleMyositis/diagnosis/physiopathology/therapyPrognosis
PMID: 26040161
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Research group Laboratoire d'immunologie translationnelle (856)
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ALLALI, Danièle, SEEBACH, Jorg Dieter. Syndrome des antisynthétases : diagnostic et traitements. In: Revue médicale suisse, 2015, vol. 11, n° 469, p. 808-812. https://archive-ouverte.unige.ch/unige:78627

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Deposited on : 2015-12-14

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