Scientific article
Open access

Finding the missing honey bee genes: lessons learned from a genome upgrade

ContributorsElsik, Christine G; Worley, Kim C; Waterhouse, Robert; Zdobnov, Evgeny; Honey Bee Genome Sequencing Consortium
Published inBMC genomics, vol. 15, 86
Publication date2014

The first generation of genome sequence assemblies and annotations have had a significant impact upon our understanding of the biology of the sequenced species, the phylogenetic relationships among species, the study of populations within and across species, and have informed the biology of humans. As only a few Metazoan genomes are approaching finished quality (human, mouse, fly and worm), there is room for improvement of most genome assemblies. The honey bee (Apis mellifera) genome, published in 2006, was noted for its bimodal GC content distribution that affected the quality of the assembly in some regions and for fewer genes in the initial gene set (OGSv1.0) compared to what would be expected based on other sequenced insect genomes.

  • Animals
  • Base Composition
  • Bees/genetics
  • Databases, Genetic
  • Genes, Insect
  • Interspersed Repetitive Sequences/genetics
  • Molecular Sequence Annotation
  • Open Reading Frames/genetics
  • Peptides/analysis
  • Sequence Analysis, RNA
  • Sequence Homology, Amino Acid
Citation (ISO format)
ELSIK, Christine G et al. Finding the missing honey bee genes: lessons learned from a genome upgrade. In: BMC genomics, 2014, vol. 15, p. 86. doi: 10.1186/1471-2164-15-86
Main files (1)
Article (Published version)
ISSN of the journal1471-2164

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