UNIGE document Scientific Article
previous document  unige:77984  next document
add to browser collection
Title

The Redox Sensor TXNL1 Plays a Regulatory Role in Fluid Phase Endocytosis

Authors
Vilbois, Francis
Published in PLOS ONE. 2007, vol. 2, no. 11, p. e1144
Abstract Small GTPases of the Rab family can cycle between a GTP- and a GDP-bound state and also between membrane and cytosol. The latter cycle is mediated by the Guanine Nucleotide Dissociation Inhibitor GDI, which can selectively extract GDP-bound Rab proteins from donor membranes, and then reload them on target membranes. In previous studies, we found that capture of the small GTPase Rab5, a key regulator of endocytic membrane traffic, by GDI is stimulated by oxidative stress via p38MAPK, resulting in increased fluid phase endocytosis.
Identifiers
Full text
Structures
Citation
(ISO format)
FELBERBAUM-CORTI, Michela et al. The Redox Sensor TXNL1 Plays a Regulatory Role in Fluid Phase Endocytosis. In: PLOS ONE, 2007, vol. 2, n° 11, p. e1144. https://archive-ouverte.unige.ch/unige:77984

130 hits

27 downloads

Update

Deposited on : 2015-12-01

Export document
Format :
Citation style :