Scientific article

Programmed assembly of rigid-rod ß-barrel pores: Thermal inversion of chirality

Published inChirality, vol. 16, no. S1, p. S28-S35
Publication date2004

The programmed assembly of p-octiphenyl rods carrying six complementary tripeptide strands was studied in the presence of bilayer membranes using circular dichroism (CD) spectroscopy. Thermal CD experiments demonstrated programmed assembly of anionic and cationic rods into supramolecules at low temperature that irreversibly transform into more stable supramolecules at intermediate and high temperature. Higher activation energies for programmed assembly with rods containing multiple guanidinium rather than ammonium cations was consistent with stabilization by guanidinium-anion complexes. Qualitative thermal inversion of supramolecular chirality during programmed assembly was detected continuously. Inversion of supramolecular chirality occurred with decreasing solvent polarity as well.

  • ß-sheet peptides
  • Circular dichroism
  • Supramolecular chemistry
  • Rigid-rod molecules
  • Vesicles
Citation (ISO format)
SAKAI, Naomi, MATILE, Stefan. Programmed assembly of rigid-rod ß-barrel pores: Thermal inversion of chirality. In: Chirality, 2004, vol. 16, n° S1, p. S28–S35. doi: 10.1002/chir.20034
Updates (1)
ISSN of the journal0899-0042

Technical informations

Creation06/21/2010 10:27:42 AM
First validation06/21/2010 10:27:42 AM
Update time03/14/2023 3:46:39 PM
Status update03/14/2023 3:46:39 PM
Last indexation10/18/2023 9:33:45 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack