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Scientific article
English

Withanolides from Withania adpressa

Contributors

Abdeljebbara, Lalla Hasna; Humam, Munir; Christen, Philippe; Jeannerat, Damien; Vitorge, Bruno; Amzazi, Saaid; Benjouad, Abdelaziz; Hostettmann, Kurt; Bekkoucheb, Khalid

Published in

Helvetica chimica acta, vol. 90, no. 2, p. 346-352

Publication date

2007

Abstract

From the leaves of Withania adpressa, a plant endemic to Sahara of Morocco and Algeria, the novel steroidal lactone (22R)-14 alpha;,15 alpha;,17ß,20ß-tetrahydroxy-1-oxowitha-2,5,24-trien-26,22-olide (= (15S,17S)-14,15,17,20-tetrahydroxy-22,26-epoxyergosta-2,5,24-triene-1,26-dione; 1), was isolated, along with three known compounds, withanolides F (2), J (3), and oleanolic acid. Their structures were mainly solved by in-depth 1D- and 2D-NMR (including ADEQUATE) experiments, as well as by HR-MS analyses and chemical evidence.

Keywords

  • Withania adpressa
  • Withanolides
  • Lactones
  • Steroids

UNIGE affiliation entities

Citation (ISO format)

ABDELJEBBARA, Lalla Hasna et al. Withanolides from Withania adpressa. In: Helvetica chimica acta, 2007, vol. 90, n° 2, p. 346–352. doi: 10.1002/hlca.200790041

Main files (1)

Article

Identifiers

Journal ISSN

0018-019X
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Technical informations

Creation

21/06/2010 10:27:30

First validation

21/06/2010 10:27:30

Update

14/03/2023 15:46:31

Status update

14/03/2023 15:46:31

Last indexation

29/10/2024 15:23:27
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