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90Yttrium PET/MR-based dosimetry after liver radioembolization (SIRT)

Publié dansClinical nuclear medicine, vol. 40, no. 4, p. 355-357
Date de publication2015
Résumé

Biodistribution and dosimetric aspects are important issues in the preparation realization of radionuclide therapies and thus play an emerging role in radioembolization of liver malignancies. Biodistribution assessment of liver selective internal radiotherapy (SIRT) has been shown feasible using PET/CT PET/magnetic resonance (MR). Whereas prospective dosimetry using 99mTc macroaggregated albumin SPECT/CT is discussed controversially, retrospective 90Y PET/CT has been shown feasible for dosimetry of SIRT in recent studies. Considering the advantages of PET/MR with regard to lesion detection radiation dose reduction compared to PET/CT, especially when repeated scanning is intended, we investigated the use of PET/MR for dosimetry of liver SIRT.

Mots-clés
  • Aged
  • Carcinoma, Hepatocellular/radiotherapy/therapy
  • Embolization, Therapeutic
  • Female
  • Humans
  • Liver Neoplasms/radiotherapy/therapy
  • Magnetic Resonance Imaging
  • Positron-Emission Tomography
  • Radiopharmaceuticals/administration & dosage/pharmacokinetics/therapeutic use
  • Radiotherapy Dosage
  • Tissue Distribution
  • Yttrium Radioisotopes/administration & dosage/pharmacokinetics/therapeutic use
Citation (format ISO)
WISSMEYER, Michael et al. 90Yttrium PET/MR-based dosimetry after liver radioembolization (SIRT). In: Clinical nuclear medicine, 2015, vol. 40, n° 4, p. 355–357. doi: 10.1097/RLU.0000000000000713
Identifiants
ISSN du journal0363-9762
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Création11.11.2015 14:08:00
Première validation11.11.2015 14:08:00
Heure de mise à jour14.03.2023 23:49:15
Changement de statut14.03.2023 23:49:15
Dernière indexation16.01.2024 19:28:11
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