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Title

In Vitro Assessment of the Tolerance Profile, the Metabolism and the Potential Depigmenting Activity of New Retinoid Derivatives

Authors
Kasraee, Behrooz
Published in Open Drug Discovery Journal. 2014, vol. 3, p. 1-9
Abstract In spite of the numerous depigmenting agents available, there is an inverse relationship between safety and efficiency. Natural retinoids exert depigmenting activities in vivo, but have a narrow therapeutic window. There is thus a need for a new class of depigmenting agents that would be both safe and useful. The aim of the study was to analyse the potential interest of new retinoid derivatives as topical depigmenting agents.
Keywords KeratinocytesMelanocytesMetabolismPharmacologyPigmentationRetinoids
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Research group La recherche en biochimie dermatologique (652)
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SORG, Olivier, KASRAEE, Behrooz, SAURAT, Jean-Hilaire. In Vitro Assessment of the Tolerance Profile, the Metabolism and the Potential Depigmenting Activity of New Retinoid Derivatives. In: Open Drug Discovery Journal, 2014, vol. 3, p. 1-9. https://archive-ouverte.unige.ch/unige:76778

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Deposited on : 2015-11-03

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