Hepatic cell proliferation plays a pivotal role in the prognosis of alcoholic hepatitis

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Title		Hepatic cell proliferation plays a pivotal role in the prognosis of alcoholic hepatitis
Authors		Lanthier, Nicolas Rubbia-Brandt, Laura Lin-Marq, Nathalie Clement, Sophie Frossard, Jean-Louis Goossens, Nicolas Hadengue, Antoine Spahr, Laurent François Joséph
Published in		Journal of hepatology. 2015, vol. 63, no. 3, p. 609-621
Abstract		The role of liver progenitor cell (LPC) expansion, known as a marker of disease severity, as well as the impact of macrophage activation on liver regeneration remains unclear in humans. We aimed to characterize the LPC and macrophage compartments in alcoholic hepatitis (AH), as well as gene expression patterns to identify predictors of a good prognosis in this setting.
Identifiers		DOI: 10.1016/j.jhep.2015.04.003 PMID: 25872168
Full text		Article (Accepted version) (3 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Research groups		Métastases du foie (657) Physiopathologie de la pancréatite aiguë (601)
Citation (ISO format)		LANTHIER, Nicolas et al. Hepatic cell proliferation plays a pivotal role in the prognosis of alcoholic hepatitis. In: Journal of hepatology, 2015, vol. 63, n° 3, p. 609-621. doi: 10.1016/j.jhep.2015.04.003 https://archive-ouverte.unige.ch/unige:76736

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Deposited on : 2015-11-02

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