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Title

Riociguat for pulmonary arterial hypertension associated with congenital heart disease

Authors
Rosenkranz, Stephan
Ghofrani, Hossein-Ardeschir
Ivy, Dunbar
Frey, Reiner
Fritsch, Arno
Weimann, Gerrit
Saleh, Soundos
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Published in Heart. 2015, vol. 101, no. 22, p. 1792-1799
Abstract The Pulmonary Arterial hyperTENsion sGC-stimulator Trial-1 (PATENT-1) was a randomised, double-blind, placebo-controlled phase III trial evaluating riociguat in patients with pulmonary arterial hypertension (PAH). PATENT-2 was an open-label long-term extension to PATENT-1. Here, we explore the efficacy and safety of riociguat in the subgroup of patients with persistent/recurrent PAH after correction of congenital heart disease (PAH-CHD) from the PATENT studies.
Identifiers
PMID: 26135803
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Article (Published version) (1.2 MB) - public document Free access
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Research group L'hypertension pulmonaire (pédiatrie) (228)
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ROSENKRANZ, Stephan et al. Riociguat for pulmonary arterial hypertension associated with congenital heart disease. In: Heart, 2015, vol. 101, n° 22, p. 1792-1799. https://archive-ouverte.unige.ch/unige:76378

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Deposited on : 2015-10-22

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