Riociguat for pulmonary arterial hypertension associated with congenital heart disease

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Title		Riociguat for pulmonary arterial hypertension associated with congenital heart disease
Authors		Rosenkranz, Stephan Ghofrani, Hossein-Ardeschir Beghetti, Maurice Ivy, Dunbar Frey, Reiner Fritsch, Arno Weimann, Gerrit Saleh, Soundos Apitz, Christian show all authors [1 - 9]
Published in		Heart. 2015, vol. 101, no. 22, p. 1792-1799
Abstract		The Pulmonary Arterial hyperTENsion sGC-stimulator Trial-1 (PATENT-1) was a randomised, double-blind, placebo-controlled phase III trial evaluating riociguat in patients with pulmonary arterial hypertension (PAH). PATENT-2 was an open-label long-term extension to PATENT-1. Here, we explore the efficacy and safety of riociguat in the subgroup of patients with persistent/recurrent PAH after correction of congenital heart disease (PAH-CHD) from the PATENT studies.
Identifiers		DOI: 10.1136/heartjnl-2015-307832 PMID: 26135803
Full text		Article (Published version) (1.2 MB) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de pédiatrie
Research group		L'hypertension pulmonaire (pédiatrie) (228)
Citation (ISO format)		ROSENKRANZ, Stephan et al. Riociguat for pulmonary arterial hypertension associated with congenital heart disease. In: Heart, 2015, vol. 101, n° 22, p. 1792-1799. https://archive-ouverte.unige.ch/unige:76378