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Treating pulmonary hypertension in pediatrics

Sekarski, Nicole
Published in Expert opinion on pharmacotherapy. 2015, vol. 16, no. 5, p. 711-726
Abstract Pulmonary hypertension is a hemodynamic condition occurring rarely in pediatrics. Nevertheless, it is associated with significant morbidity and mortality. When characterized by progressive pulmonary vascular structural changes, the disease is called pulmonary arterial hypertension (PAH). It results in increased pulmonary vascular resistance and eventual right ventricular failure. In the vast majority of cases, pediatric PAH is idiopathic or associated with congenital heart disease, and, contrary to adult PAH, is rarely associated with connective tissue, portal hypertension, HIV infection or thromboembolic disease.
Keywords ChildDrug Therapy, CombinationEndothelin Receptor Antagonists/therapeutic useEpoprostenol/analogs & derivatives/therapeutic useHIV InfectionsHumansHypertension, Pulmonary/classification/drug therapyPhosphodiesterase 5 Inhibitors/therapeutic useQuality of Life
PMID: 25665593
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Research group L'hypertension pulmonaire (pédiatrie) (228)
(ISO format)
LADOR, Frédéric, SEKARSKI, Nicole, BEGHETTI, Maurice. Treating pulmonary hypertension in pediatrics. In: Expert opinion on pharmacotherapy, 2015, vol. 16, n° 5, p. 711-726. doi: 10.1517/14656566.2015.1013937 https://archive-ouverte.unige.ch/unige:76340

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Deposited on : 2015-10-21

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