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Scientific article
English

Treating pulmonary hypertension in pediatrics

Contributors

Lador, Frédéric; Sekarski, Nicole; Beghetti, Maurice

Published in

Expert opinion on pharmacotherapy, vol. 16, no. 5, p. 711-726

Publication date

2015

Abstract

Pulmonary hypertension is a hemodynamic condition occurring rarely in pediatrics. Nevertheless, it is associated with significant morbidity and mortality. When characterized by progressive pulmonary vascular structural changes, the disease is called pulmonary arterial hypertension (PAH). It results in increased pulmonary vascular resistance and eventual right ventricular failure. In the vast majority of cases, pediatric PAH is idiopathic or associated with congenital heart disease, and, contrary to adult PAH, is rarely associated with connective tissue, portal hypertension, HIV infection or thromboembolic disease.

Keywords

  • Child
  • Drug Therapy, Combination
  • Endothelin Receptor Antagonists/therapeutic use
  • Epoprostenol/analogs & derivatives/therapeutic use
  • HIV Infections
  • Humans
  • Hypertension, Pulmonary/classification/drug therapy
  • Phosphodiesterase 5 Inhibitors/therapeutic use
  • Quality of Life

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

LADOR, Frédéric, SEKARSKI, Nicole, BEGHETTI, Maurice. Treating pulmonary hypertension in pediatrics. In: Expert opinion on pharmacotherapy, 2015, vol. 16, n° 5, p. 711–726. doi: 10.1517/14656566.2015.1013937

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1465-6566
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1downloads

Technical informations

Creation

18/10/2015 15:36:00

First validation

18/10/2015 15:36:00

Update

14/03/2023 23:44:11

Status update

14/03/2023 23:44:10

Last indexation

31/10/2024 01:37:52
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