Scientific article
English

Epileptic activity is a surrogate for an underlying etiology and stopping the activity has a limited impact on developmental outcome

Published inEpilepsia, vol. 56, no. 10, p. 1477-1481
Publication date2015
Abstract

The concept of epileptic encephalopathy is important in clinical practice, but its relevance to an individual must be assessed in the appropriate context. Except in rare situations, epileptic activity is a surrogate for an underlying etiology, and stopping the activity has a limited impact on developmental outcome. Labeling a group of epilepsies as "the epileptic encephalopathies," risks minimizing the impact of epileptic activity on cognition and behavior more widely in epilepsy. Similarly, describing the encephalopathy associated with many infantile onset epilepsies as "epileptic" may be misleading. Finally, concentrating on the epileptic activity alone and not considering the wider consequences of the underlying etiology on cognitive and behavioral development, may focus research efforts and the search for improved therapies on too narrow a target. Therefore, epileptic encephalopathies should not be considered as a specific group of epilepsies but, rather, the concept of epileptic encephalopathy should be applicable to all types of epilepsies and epilepsy syndromes, whenever it is relevant in the clinical course of a particular individual, at any age.

Citation (ISO format)
KORFF, Christian, BRUNKLAUS, Andreas, ZUBERI, Sameer M. Epileptic activity is a surrogate for an underlying etiology and stopping the activity has a limited impact on developmental outcome. In: Epilepsia, 2015, vol. 56, n° 10, p. 1477–1481. doi: 10.1111/epi.13105
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0013-9580
480views
1downloads

Technical informations

Creation16/09/2015 16:54:00
First validation16/09/2015 16:54:00
Update time15/03/2023 00:44:06
Status update15/03/2023 00:44:06
Last indexation31/10/2024 02:37:47
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack