UNIGE document Scientific Article
previous document  unige:76329  next document
add to browser collection
Title

Pneumococcal polysaccharide vaccination in adults undergoing immunosuppressive treatment for inflammatory diseases--a longitudinal study

Authors
Gerstel, p
Seebach, Joerg Dieter
Published in Arthritis Research and Therapy. 2015, vol. 17, p. 151
Abstract Patients undergoing immunosuppressive therapy are at increased risk of infection. Community-acquired pneumonia and invasive pneumococcal disease account for substantial morbidity and mortality in this population and may be prevented by vaccination. Ideally, immunization to pneumococcal antigens should take place before the start of immunosuppressive treatment. Often, however, the treatment cannot be delayed. Little is known about the efficacy of pneumococcal vaccines during immunosuppressive treatment. The objectives of this study were to determine the percentage of vaccine-naïve, immunosuppressed adults with inflammatory diseases seroprotected against Streptococcus pneumoniae and to assess factors associated with the immunogenicity, clinical impact and safety of 23-valent pneumococcal polysaccharide vaccine (PPV) in seronegative subjects.
Identifiers
PMID: 26048579
Full text
Article (Published version) (1.2 MB) - public document Free access
Structures
Research groups Centre de vaccinologie et d'immunologie néonatale (177)
Mécanisme de l'inflammation articulaire (44)
Epidémiologie clinique (115)
Citation
(ISO format)
FISCHER, Lara et al. Pneumococcal polysaccharide vaccination in adults undergoing immunosuppressive treatment for inflammatory diseases--a longitudinal study. In: Arthritis Research and Therapy, 2015, vol. 17, p. 151. https://archive-ouverte.unige.ch/unige:76329

128 hits

247 downloads

Update

Deposited on : 2015-10-21

Export document
Format :
Citation style :