UNIGE document Scientific Article
previous document  unige:75949  next document
add to browser collection
Title

Concanavalin A electrochemical sensor based on the surface blocking principle at an ion-selective polymeric membrane

Authors
Published in Microchimica Acta. 2015, vol. 182, no. 1-2, p. 129-137
Abstract We report on a new electrochemical sensor for Concanavalin A. It is based on blocking the surface of plasticized PVC membranes that were covalently modified with D-mannose using click chemistry. The interaction of D-mannose with Concanavalin A on the surface perturbs the flux of a marker ion for which the ion-selective membrane is responsive, and this results in a change in the electrochemical signal. The sensor was characterized using a variety of electrochemical protocols, and results were confirmed by quartz crystal microbalance experiments. The lowest limit of detection (10 μg mL−1) was obtained using a membrane containing a cation exchanger and tetrabutylammonium ion as the marker ion.
Keywords BiosensorConcanavalinAClick chemistryIon selective electrodesChronopotentiometry
Identifiers
Full text
Article (Published version) (260 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://link.springer.com/10.1007/s00604-014-1309-3
Structures
Research group Groupe Bakker
Citation
(ISO format)
PAWLAK, Marcin, MISTLBERGER, Günter, BAKKER, Eric. Concanavalin A electrochemical sensor based on the surface blocking principle at an ion-selective polymeric membrane. In: Microchimica Acta, 2015, vol. 182, n° 1-2, p. 129-137. https://archive-ouverte.unige.ch/unige:75949

173 hits

0 download

Update

Deposited on : 2015-10-12

Export document
Format :
Citation style :