We report here on a portable, custom-made instrument for decentralized measurements with ionophore based electrodes. It allows one to perform most common electrochemical protocols based on applied current or potential as well as zero current potentiometry measurements. Each protocol is customizable via a programmable interface by use of either an external PC or a touch screen panel on the device. The programmable interface provides flexibility to trigger peripheral devices for the additional implementation of actuators, pumps and other external devices in the electrochemical routines. To characterize the electronic performance of the instrument, three different electrochemical protocols were used with ionophore based electrodes and compared with a commercial work station: (1) open circuit potentiometric measurements with calcium ion-selective membranes; (2) chronoamperometry based on three successive pulses with simultaneous control of fluidic delivery by a peristaltic pump and switching valve, followed by on board current integration to obtain a coulometric readout; (3) a chronopotentiometric protocol using protamine selective membranes with current pulses of 5-s duration, including an automatic computation of the time-derivative to find the transition time as the analytical signal. At 500 g, the instrument is portable yet sufficiently versatile for performing and analyzing most electrochemical measurements without the need for an external computer. It may become an attractive tool for applications in environmental and clinical analysis where field portability, flexibility and integration are desired.