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Title

Structural and functional connectivity in the default mode network in 22q11.2 deletion syndrome

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Published in Journal of Neurodevelopmental Disorders. 2015, vol. 7, no. 1, p. 23
Abstract The neural endophenotype associated with 22q11.2 deletion syndrome (22q11DS) includes deviant cortical development and alterations in brain connectivity. Resting-state functional magnetic resonance imaging (fMRI) findings also reported disconnectivity within the default mode network (DMN). In this study, we explored the relationship between functional and structural DMN connectivity and their changes with age in patients with 22q11DS in comparison to control participants. Given previous evidence of an association between DMN disconnectivity and the manifestation of psychotic symptoms, we further investigated this relationship in our group of patients with 22q11DS.
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PMID: 26236404
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Research groups Laboratoire d'imagerie et de psychopathologie développementale (693)
Traitement d'images médicales (893)
Unité de psychologie clinique de l'adolescence (UPCA)
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PADULA, Maria et al. Structural and functional connectivity in the default mode network in 22q11.2 deletion syndrome. In: Journal of Neurodevelopmental Disorders, 2015, vol. 7, n° 1, p. 23. https://archive-ouverte.unige.ch/unige:75910

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Deposited on : 2015-10-09

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