en
Scientific article
English

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

Published inJAMA, vol. 313, no. 19, p. 1924-1938
Publication date2015
Abstract

Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.

Keywords
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Amyloid beta-Peptides/analysis
  • Apolipoprotein E4/genetics
  • Biological Markers/analysis
  • Brain/pathology
  • Cerebrospinal Fluid/chemistry
  • Dementia/pathology
  • Female
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Mild Cognitive Impairment/pathology
  • Positron-Emission Tomography
  • Prevalence
  • Risk Factors
Citation (ISO format)
JANSEN, Willemijn J et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. In: JAMA, 2015, vol. 313, n° 19, p. 1924–1938. doi: 10.1001/jama.2015.4668
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0098-7484
508views
2downloads

Technical informations

Creation08/20/2015 10:51:00 AM
First validation08/20/2015 10:51:00 AM
Update time03/14/2023 11:40:58 PM
Status update03/14/2023 11:40:57 PM
Last indexation01/16/2024 7:07:09 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack