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Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

Jansen, Willemijn J
Ossenkoppele, Rik
Knol, Dirk L
Tijms, Betty M
Scheltens, Philip
Verhey, Frans R J
Visser, Pieter Jelle
CollaborationWith : Frisoni, Giovanni / Popp, Julius
Published in JAMA (Journal of the American Medical Association). 2015, vol. 313, no. 19, p. 1924-1938
Abstract Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.
Keywords AdultAge FactorsAgedAged, 80 and overAmyloid beta-Peptides/analysisApolipoprotein E4/geneticsBiological Markers/analysisBrain/pathologyCerebrospinal Fluid/chemistryDementia/pathologyFemaleGenotypeHumansMaleMiddle AgedMild Cognitive Impairment/pathologyPositron-Emission TomographyPrevalenceRisk Factors
PMID: 25988462
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Article (Published version) (733 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research groups Troubles de mémoire et maladie d'Alzeimer (935)
Neuropsychiatrie et Biomarqueurs de la maladie d'Alzheimer (991)
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JANSEN, Willemijn J et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. In: JAMA (Journal of the American Medical Association), 2015, vol. 313, n° 19, p. 1924-1938. doi: 10.1001/jama.2015.4668 https://archive-ouverte.unige.ch/unige:75878

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Deposited on : 2015-10-08

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