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Title

Group A beta-hemolytic streptococcus meningitis: clinical and microbiological features of nine cases
Authors
Sommer, Richard Andréas
Rohner, Peter
Garbino, Jorge
Auckenthaler, Raymond
Malinverni, R.
Lew, Daniel Pablo
Kaiser, Laurent
Published in Clinical infectious diseases. 1999, vol. 29, no. 4, p. 929-931
Abstract Group A beta-hemolytic streptococcus (GAS) meningitis is a rare disease in adults. We conducted a retrospective study to describe clinical and microbiological features of nine cases of GAS meningitis in Switzerland. Of nine patients, six had neurosurgical conditions, and five had upper respiratory tract infections. Eight cases were community-acquired. The outcome of GAS meningitis was favorable; only one patient died of neurosurgical complications. No patient presented with toxic shock syndrome. Serotyping failed to reveal a dominant strain, and genotyping revealed that two strains carried the gene encoding the streptococcal pyrogenic exotoxin C and that one strain carried the gene encoding the streptococcal pyrogenic exotoxin A. Our observations suggest that GAS meningitis in adults is associated with neurosurgical conditions and/or an upper respiratory tract infection.
Keywords Adolescent — Adult — Female — Humans — Male — Meningitis, Bacterial/ etiology/microbiology — Middle Aged — Streptococcal Infections/ etiology/microbiology — Streptococcus pyogenes/pathogenicity — Virulence
Identifiers
PMID: 10589913
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Article - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Citation
(ISO format) 		SOMMER, Richard Andréas et al. Group A beta-hemolytic streptococcus meningitis: clinical and microbiological features of nine cases. In: Clinical infectious diseases, 1999, vol. 29, n° 4, p. 929-931. doi: 10.1086/520461 https://archive-ouverte.unige.ch/unige:7586

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Deposited on : 2010-06-21

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