Appropriateness and long-term discontinuation rate of biological therapies in ulcerative colitis

Maillard, Michel H; Bortolotti, Murielle; Vader, John-Paul; Mottet, Christian; Schoepfer, Alain; Gonvers, Jean-Jacques; Burnand, Bernard; Froehlich, Florian; Michetti, Pierre; Pittet, Valérie

doi:10.1016/j.crohns.2013.12.026

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Title		Appropriateness and long-term discontinuation rate of biological therapies in ulcerative colitis
Authors		Maillard, Michel H Bortolotti, Murielle Vader, John-Paul Mottet, Christian Schoepfer, Alain Gonvers, Jean-Jacques Burnand, Bernard Froehlich, Florian Michetti, Pierre Pittet, Valérie show all authors [1 - 10]
Collaboration		Swiss IBD Cohort Study Group With : Belli, Dominique Charles / Zamora, Samuel Antonio
Published in		Journal of Crohn's and colitis. 2014, vol. 8, no. 8, p. 825-834
Abstract		Anti-TNFα agents are commonly used for ulcerative colitis (UC) therapy in the event of non-response to conventional strategies or as colon-salvaging therapy. The objectives were to assess the appropriateness of biological therapies for UC patients and to study treatment discontinuation over time, according to appropriateness of treatment, as a measure of outcome.
Keywords		Adolescent — Adult — Aged — Colitis, Ulcerative/drug therapy — Female — Humans — Immunologic Factors/adverse effects/therapeutic use — Inappropriate Prescribing/statistics & numerical data — Longitudinal Studies — Male — Middle Aged — Treatment Outcome — Tumor Necrosis Factor-alpha/antagonists & inhibitors — Young Adult
Identifiers		DOI: 10.1016/j.crohns.2013.12.026 PMID: 24462322
Full text		Article (Published version) (595 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research group		Gastroentérologie et transplantation (pédiatrie) (181)
Citation (ISO format)		MAILLARD, Michel H et al. Appropriateness and long-term discontinuation rate of biological therapies in ulcerative colitis. In: Journal of Crohn's and Colitis, 2014, vol. 8, n° 8, p. 825-834. doi: 10.1016/j.crohns.2013.12.026 https://archive-ouverte.unige.ch/unige:74910