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Title

Traitement chirurgical de l'emphysème sévère: transplantation pulmonaire ou réduction de volume?
Authors
Licker, Marc
De Perrot, Marc Eugène Antoine
Schweizer, A
Tschopp, Jean-Marie
Robert, John
Hohn, Laurent
Rochat, Thierry
Spiliopoulos, Anastase
Published in Schweizerische medizinische Wochenschrift. 1998, vol. 128, no. 11, p. 409-15
Abstract In recent years, lung transplantation (LT) and volume reduction surgery (LVRS) have been proposed for selected patients with end-stage pulmonary emphysema. Retrospectively, we analyzed the perioperative time course of 30 patients with emphysema who underwent either LVRS (n = 17) or LT (n = 13). In the LVRS group, patients were significantly older, presented less severe functional disability and all but one could be extubated at the end of surgery. In contrast, patients undergoing LT required postoperative mechanical ventilation (19 +/- 11 hrs) and had a prolonged hospital stay (37 [25-60] days vs 19 [11-42] days in LVRS patients) due to reperfusion lung edema, infection, hemorrhage and acute rejection. Six months postoperatively, forced expiratory volume in 1 second was improved and was significantly larger after LT compared with LVRS (+200% vs +63%). Our preliminary results suggest that, although LT produces greater functional improvement, LVRS is associated with lower surgical risk and is an alternative therapy in selected patients with severe emphysema.
Keywords Aged — Female — Humans — Length of Stay — Lung Transplantation/physiology — Lung Volume Measurements — Male — Middle Aged — Pneumonectomy — Postoperative Complications/etiology/physiopathology — Pulmonary Emphysema/physiopathology/surgery — Respiratory Insufficiency/etiology/physiopathology — Retrospective Studies — Treatment Outcome
Identifiers
PMID: 9561587
Full text
Article (Published version) (4.2 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Faculté de médecine / Section de médecine clinique / Département de chirurgie
Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences
Research groups Dysfonctions cardio-pulmonaires et cérébrales (278)
Pneumologie Clinique (576)
Citation
(ISO format) 		LICKER, Marc et al. Traitement chirurgical de l'emphysème sévère: transplantation pulmonaire ou réduction de volume?. In: Schweizerische medizinische Wochenschrift, 1998, vol. 128, n° 11, p. 409-15. https://archive-ouverte.unige.ch/unige:74712

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Deposited on : 2015-08-17

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