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Title

Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury

Authors
Prost, Jean-Christophe
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Published in PLOS ONE. 2015, vol. 10, no. 3, p. e0119664
Abstract New evidence shows that high density lipoproteins (HDL) have protective effects beyond their role in reverse cholesterol transport. Reconstituted HDL (rHDL) offer an attractive means of clinically exploiting these novel effects including cardioprotection against ischemia reperfusion injury (IRI). However, basic rHDL composition is limited to apolipoprotein AI (apoAI) and phospholipids; addition of bioactive compound may enhance its beneficial effects.
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PMID: 25781943
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Article (Published version) (1.1 MB) - public document Free access
Structures
Research groups Lipoprotéines sériques (598)
Chimie et protéomique clinique (270)
L'athérosclérose et ses complications cliniques (591)
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BRULHART-MEYNET, Marie-claude et al. Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. In: PLOS ONE, 2015, vol. 10, n° 3, p. e0119664. https://archive-ouverte.unige.ch/unige:74659

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Deposited on : 2015-08-12

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