Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012

Yang, Wan-Lin; Kouyos, Roger; Scherrer, Alexandra U; Böni, Jürg; Shah, Cyril; Yerly Ferrillo, Sabine; Klimkait, Thomas; Aubert, Vincent; Furrer, Hansjakob; Battegay, Manuel; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro; Held, Leonhard; Ledergerber, Bruno; Günthard, Huldrych F

doi:10.1093/infdis/jiv012

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Title		Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012
Authors		Yang, Wan-Lin Kouyos, Roger Scherrer, Alexandra U Böni, Jürg Shah, Cyril Yerly Ferrillo, Sabine Klimkait, Thomas Aubert, Vincent Furrer, Hansjakob Battegay, Manuel Cavassini, Matthias Bernasconi, Enos Vernazza, Pietro Held, Leonhard Ledergerber, Bruno Günthard, Huldrych F show all authors [1 - 16]
Published in		The Journal of Infectious Diseases. 2015, vol. 212, no. 1, p. 28-38
Abstract		Transmitted human immunodeficiency virus type 1 (HIV) drug resistance (TDR) mutations are transmitted from nonresponding patients (defined as patients with no initial response to treatment and those with an initial response for whom treatment later failed) or from patients who are naive to treatment. Although the prevalence of drug resistance in patients who are not responding to treatment has declined in developed countries, the prevalence of TDR mutations has not. Mechanisms causing this paradox are poorly explored.
Identifiers		DOI: 10.1093/infdis/jiv012 PMID: 25576600
Full text		Article (Published version) (795 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine
Research group		Groupe Laurent Kaiser (virologie clinique) (668)
Citation (ISO format)		YANG, Wan-Lin et al. Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012. In: The Journal of Infectious Diseases, 2015, vol. 212, n° 1, p. 28-38. doi: 10.1093/infdis/jiv012 https://archive-ouverte.unige.ch/unige:74657