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Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012 |
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Published in | The Journal of Infectious Diseases. 2015, vol. 212, no. 1, p. 28-38 | |
Abstract | Transmitted human immunodeficiency virus type 1 (HIV) drug resistance (TDR) mutations are transmitted from nonresponding patients (defined as patients with no initial response to treatment and those with an initial response for whom treatment later failed) or from patients who are naive to treatment. Although the prevalence of drug resistance in patients who are not responding to treatment has declined in developed countries, the prevalence of TDR mutations has not. Mechanisms causing this paradox are poorly explored. | |
Identifiers | PMID: 25576600 | |
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Research group | Groupe Laurent Kaiser (virologie clinique) (668) | |
Citation (ISO format) | YANG, Wan-Lin et al. Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012. In: The Journal of Infectious Diseases, 2015, vol. 212, n° 1, p. 28-38. doi: 10.1093/infdis/jiv012 https://archive-ouverte.unige.ch/unige:74657 |