Decreased exhaled nitric oxide may be a marker of cardiopulmonary bypass-induced injury

Beghetti, Maurice; Silkoff, P E; Caramori, M; Holtby, H M; Slutsky, A S; Adatia, I

doi:10.1016/S0003-4975(98)00447-0

Scientific article

English

Decreased exhaled nitric oxide may be a marker of cardiopulmonary bypass-induced injury

ContributorsBeghetti, Maurice; Silkoff, P E; Caramori, M; Holtby, H M; Slutsky, A S; Adatia, I

Published inThe annals of thoracic surgery, vol. 66, no. 2, p. 532-534

Publication date1998

Abstract

Nitric oxide is an endothelium-derived vasodilator. Cardiopulmonary bypass may induce transient pulmonary endothelial dysfunction with decreased nitric oxide release that contributes to postoperative pulmonary hypertension and lung injury. Exhaled nitric oxide levels may reflect, in part, endogenous production from the pulmonary vascular endothelium.

Keywords

Biological Markers/analysis
Cardiopulmonary Bypass/adverse effects
Child
Child, Preschool
Endothelium, Vascular/metabolism
Female
Heart Defects, Congenital/surgery
Humans
Infant, Newborn
Male
Nitric Oxide/analysis/biosynthesis
Respiration
Time Factors

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research groups

L'hypertension pulmonaire (pédiatrie) (228)

Citation (ISO format)

BEGHETTI, Maurice et al. Decreased exhaled nitric oxide may be a marker of cardiopulmonary bypass-induced injury. In: The annals of thoracic surgery, 1998, vol. 66, n° 2, p. 532–534. doi: 10.1016/S0003-4975(98)00447-0

Article (Published version)

Identifiers

PID : unige:74625
DOI : 10.1016/S0003-4975(98)00447-0
PMID : 9725398

ISSN of the journal0003-4975

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Decreased exhaled nitric oxide may be a marker of cardiopulmonary bypass-induced injury

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