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Rôle de la scintigraphie au DMSA dans la prise en charge des pyélonéphrites de l'enfant

Published in Archives de pédiatrie. 1998, vol. 5 Suppl 3, p. 285S-289S
Abstract Pyelonephritis in children may lead to irreversible renal damage and eventually to arterial hypertension and renal insufficiency. Inflammation plays a central role in the pathogenesis of pyelonephritis. Dimercaptosuccinic acid (DMSA) scintigraphy permits detection of acute renal lesions and renal scars with high sensitivity and specificity. In our experience 60% of patients who had acute renal lesions on DMSA scintigraphy during pyelonephritis develop scars. Young age appears to be not a risk factor, as in our experience 70% of children older than 5 years develop scars compared to 40% for children younger than 1 year. In addition, only 40% of patients who develop scars have vesicoureteral reflux. DMSA scintigraphy may provide answers to important clinical questions: what is the optimal length of treatment of pyelonephritis? Is parenteral treatment necessary? What is the best treatment of vesicoureteral reflux? DMSA scintigraphy permits therapeutical decision-making according to the renal involvement in each of our patients.
Keywords Acute DiseaseAdolescentChildChild, PreschoolFemaleHumansInfantMalePatient Care PlanningPyelonephritis/etiology/radionuclide imagingRisk FactorsTechnetium Tc 99m Dimercaptosuccinic Acid/diagnostic use
PMID: 9759320
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Research group Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)
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GIRARDIN, Eric, BENADOR, Daivy. Rôle de la scintigraphie au DMSA dans la prise en charge des pyélonéphrites de l'enfant. In: Archives de pédiatrie, 1998, vol. 5 Suppl 3, p. 285S-289S. doi: 10.1016/S0929-693X(98)80151-6 https://archive-ouverte.unige.ch/unige:74600

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