Generation of a recombinant Gag virus-like-particle panel for the evaluation of p24 antigen detection by diagnostic HIV tests

Vetter, Beatrice N; Orlowski, Vanessa; Fransen, Katrien; Niederhauser, Christoph; Aubert, Vincent; Brandenberger, Marcel; Ciardo, Diana; Dollenmaier, Günter; Klimkait, Thomas; Regenass, Stephan; Schmid, Patrick; Schottstedt, Volkmar; Suter-Riniker, Franziska; Yerly Ferrillo, Sabine; Shah, Cyril; Böni, Jürg; Schüpbach, Jörg

doi:10.1371/journal.pone.0111552

Scientific article

English

Generation of a recombinant Gag virus-like-particle panel for the evaluation of p24 antigen detection by diagnostic HIV tests

ContributorsVetter, Beatrice N; Orlowski, Vanessa; Fransen, Katrien; Niederhauser, Christoph; Aubert, Vincent; Brandenberger, Marcel; Ciardo, Diana; Dollenmaier, Günter; Klimkait, Thomas; Regenass, Stephan; Schmid, Patrick; Schottstedt, Volkmar; Suter-Riniker, Franziska; Yerly Ferrillo, Sabine; Shah, Cyril; Böni, Jürg; Schüpbach, Jörg

Published inPloS one, vol. 9, no. 10, e111552

Publication date2014

Abstract

Detection of HIV-1 p24 antigen permits early identification of primary HIV infection and timely intervention to limit further spread of the infection. Principally, HIV screening should equally detect all viral variants, but reagents for a standardised test evaluation are limited. Therefore, we aimed to create an inexhaustible panel of diverse HIV-1 p24 antigens.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Groupe Laurent Kaiser (virologie clinique) (668)

Citation (ISO format)

VETTER, Beatrice N et al. Generation of a recombinant Gag virus-like-particle panel for the evaluation of p24 antigen detection by diagnostic HIV tests. In: PloS one, 2014, vol. 9, n° 10, p. e111552. doi: 10.1371/journal.pone.0111552

Article (Published version)

CC BY

Identifiers

PID : unige:74509
DOI : 10.1371/journal.pone.0111552
PMID : 25343245

Journal ISSN1932-6203

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Generation of a recombinant Gag virus-like-particle panel for the evaluation of p24 antigen detection by diagnostic HIV tests

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