UNIGE document Scientific Article
previous document  unige:74482  next document
add to browser collection
Title

Higher rates of metabolic syndrome among women taking zidovudine as compared to tenofovir in rural Africa: preliminary data from the CART-1 study

Authors
Labhardt, Niklaus Daniel
Cheleboi, Molisana
Faturyiele, Olatunbosun
Motlatsi, Mokete M
Pfeiffer, Karolin
Lejone, Thabo Ismael
Muser, Jürgen
show hidden authors show all authors [1 - 11]
Published in Journal of the International AIDS society. 2014, vol. 17, no. 4 Suppl 3, p. 19552
Abstract Due to its side effects stavudine (D4T) has been replaced by zidovudine (AZT) and tenofovir (TDF) in most low- and middle-income countries (LMICs). In 2014 about 38% of adult first-line regimens contain AZT and 62% TDF [1]. Whereas the unfavourable metabolic outcomes of D4T in comparison to TDF have been described extensively, studies from LMICs comparing metabolic profiles between patients on AZT and TDF are scarce. Given the high number of patients in LMICs still taking AZT, data on their metabolic profile are needed. We present rates of metabolic syndrome (MS) in adult patients taking either AZT- or TDF-containing first-line, non-nucleoside reverse transcriptase (NNRTI)-based regimens.
Identifiers
PMID: 25394059
Full text
Structures
Citation
(ISO format)
LABHARDT, Niklaus Daniel et al. Higher rates of metabolic syndrome among women taking zidovudine as compared to tenofovir in rural Africa: preliminary data from the CART-1 study. In: Journal of the International AIDS society, 2014, vol. 17, n° 4 Suppl 3, p. 19552. https://archive-ouverte.unige.ch/unige:74482

192 hits

26 downloads

Update

Deposited on : 2015-08-06

Export document
Format :
Citation style :