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Scientific article
English

Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children

Published inThe Pediatric infectious disease journal, vol. 33, no. 12, p. 1285-1287
Publication date2014
Abstract

The clinical course of rhinovirus (RV)-associated wheezing illnesses is difficult to predict. We measured lactate dehydrogenase concentrations, RV load, antiviral and proinflammatory cytokines in nasal washes obtained from 126 preschool children with RV wheezy bronchitis. lactate dehydrogenase values were inversely associated with subsequent need for oxygen therapy. lactate dehydrogenase may be a useful biomarker predicting disease severity in RV wheezy bronchitis.

Keywords
  • Biological Markers/analysis
  • Bronchitis/diagnosis/pathology
  • Child, Preschool
  • Cytokines/analysis
  • Female
  • Humans
  • Infant
  • L-Lactate Dehydrogenase/analysis
  • Male
  • Nasal Mucosa/chemistry
  • Picornaviridae Infections/diagnosis/pathology
  • Retrospective Studies
  • Rhinovirus/isolation & purification
  • Severity of Illness Index
  • Viral Load
Citation (ISO format)
CANGIANO, Giulia et al. Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children. In: The Pediatric infectious disease journal, 2014, vol. 33, n° 12, p. 1285–1287. doi: 10.1097/INF.0000000000000420
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Article (Published version)
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Identifiers
ISSN of the journal0891-3668
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