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Title

Antimicrobial susceptibility of bacterial pathogens in the oropharynx of healthy children

Authors
Strautman, G
Published in European Journal of Clinical Microbiology & Infectious Diseases. 1999, vol. 18, no. 3, p. 217-20
Abstract In a study to determine the prevalence and antimicrobial susceptibility of bacterial pathogens in the oropharynx of healthy children, throat swabs obtained from 1765 children were cultured and the organisms recovered tested by the disk diffusion method and the E test. Six hundred ninety-one children (39.1%) harbored Haemophilus influenzae, 112 (6.3%) Streptococcus pyogenes, 73 (4.1%) Moraxella catarrhalis, 52 (2.9%) Streptococcus pneumoniae, and 50 (2.8%) Neisseria meningitidis in their oropharynx. The rate of penicillin resistance was 2%, 0%, and 12%, respectively, for Streptococcus pneumoniae, Streptococcus pyogenes, and Neisseria meningitidis. Ampicillin resistance was observed in 8.6% of Haemophilus influenzae strains and 78% of Moraxella catarrhalis strains and was associated with the presence of beta-lactamase, except in one strain of Haemophilus influenzae. Five (4.4%) isolates of Streptococcus pyogenes were resistant to macrolides. The low level of resistance observed in this area contrasts with the high rates reported in the literature.
Keywords Anti-Bacterial Agents/pharmacologyChildDrug Resistance, MicrobialHaemophilus influenzae/drug effects/isolation & purificationHumansMicrobial Sensitivity TestsMoraxella (Branhamella) catarrhalis/drug effects/isolation & purificationNeisseria meningitidis/drug effects/isolation & purificationOropharynx/microbiologyStreptococcus pneumoniae/drug effects/isolation & purificationStreptococcus pyogenes/drug effects/isolation & purification
Identifiers
PMID: 10357059
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Structures
Research group Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
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(ISO format)
LIASSINE, Nadine et al. Antimicrobial susceptibility of bacterial pathogens in the oropharynx of healthy children. In: European Journal of Clinical Microbiology & Infectious Diseases, 1999, vol. 18, n° 3, p. 217-20. https://archive-ouverte.unige.ch/unige:74351

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Deposited on : 2015-07-27

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