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The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow's milk |
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Published in | Journal of Allergy and Clinical Immunology. 1999, vol. 103, no. 5 Pt 1, p. 931-6 | |
Abstract | It has been shown in mice that the integrin alpha4beta7 directs the migration of memory T cells into the gut-associated lymphoid tissue. However, little is known about T-cell homing mechanisms in children with food allergies. | |
Keywords | CD4-Positive T-Lymphocytes/metabolism — Cells, Cultured — Child — Child, Preschool — Female — Fluorescence — Humans — Infant — Integrins/biosynthesis — L-Selectin/biosynthesis — Lactoglobulins/pharmacology — Lymphocyte Activation/drug effects — Male — Milk Hypersensitivity/blood — T-Lymphocytes/immunology/metabolism — Time Factors | |
Identifiers | PMID: 10329831 | |
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Research group | Pathogenèse et traitement des allergies alimentaires (191) | |
Citation (ISO format) | EIGENMANN, Philippe, TROPIA, Laurence, HAUSER, Conrad. The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow's milk. In: Journal of Allergy and Clinical Immunology, 1999, vol. 103, n° 5 Pt 1, p. 931-6. https://archive-ouverte.unige.ch/unige:74319 |