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Scientific article
English

The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow's milk

Published inJournal of allergy and clinical immunology, vol. 103, no. 5 Pt 1, p. 931-936
Publication date1999
Abstract

It has been shown in mice that the integrin alpha4beta7 directs the migration of memory T cells into the gut-associated lymphoid tissue. However, little is known about T-cell homing mechanisms in children with food allergies.

Keywords
  • CD4-Positive T-Lymphocytes/metabolism
  • Cells, Cultured
  • Child
  • Child, Preschool
  • Female
  • Fluorescence
  • Humans
  • Infant
  • Integrins/biosynthesis
  • L-Selectin/biosynthesis
  • Lactoglobulins/pharmacology
  • Lymphocyte Activation/drug effects
  • Male
  • Milk Hypersensitivity/blood
  • T-Lymphocytes/immunology/metabolism
  • Time Factors
Citation (ISO format)
EIGENMANN, Philippe, TROPIA, Laurence, HAUSER, Conrad. The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow’s milk. In: Journal of allergy and clinical immunology, 1999, vol. 103, n° 5 Pt 1, p. 931–936. doi: 10.1016/S0091-6749(99)70441-0
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Article (Published version)
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Identifiers
ISSN of the journal0091-6749
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