The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow&#039;s milk

Eigenmann, Philippe; Tropia, Laurence; Hauser, Conrad

doi:10.1016/S0091-6749(99)70441-0

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Title		The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow's milk
Authors		Eigenmann, Philippe Tropia, Laurence Hauser, Conrad
Published in		Journal of Allergy and Clinical Immunology. 1999, vol. 103, no. 5 Pt 1, p. 931-6
Abstract		It has been shown in mice that the integrin alpha4beta7 directs the migration of memory T cells into the gut-associated lymphoid tissue. However, little is known about T-cell homing mechanisms in children with food allergies.
Keywords		CD4-Positive T-Lymphocytes/metabolism — Cells, Cultured — Child — Child, Preschool — Female — Fluorescence — Humans — Infant — Integrins/biosynthesis — L-Selectin/biosynthesis — Lactoglobulins/pharmacology — Lymphocyte Activation/drug effects — Male — Milk Hypersensitivity/blood — T-Lymphocytes/immunology/metabolism — Time Factors
Identifiers		DOI: 10.1016/S0091-6749(99)70441-0 PMID: 10329831
Full text		Article (Published version) (89 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique Faculté des sciences / Section de biologie / Département de biologie moléculaire
Research group		Pathogenèse et traitement des allergies alimentaires (191)
Citation (ISO format)		EIGENMANN, Philippe, TROPIA, Laurence, HAUSER, Conrad. The mucosal adhesion receptor alpha4beta7 integrin is selectively increased in lymphocytes stimulated with beta-lactoglobulin in children allergic to cow's milk. In: Journal of Allergy and Clinical Immunology, 1999, vol. 103, n° 5 Pt 1, p. 931-6. doi: 10.1016/S0091-6749(99)70441-0 https://archive-ouverte.unige.ch/unige:74319