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Fungal endocarditis in critically ill children

Published in European Journal of Pediatrics. 1999, vol. 158, no. 4, p. 275-80
Abstract All cases of infective endocarditis occurring from January 1990 to December 1996 at our institution were reviewed, with a special focus on fungal endocarditis. Five critically ill children with fungal endocarditis and eleven children with bacterial endocarditis were recorded. The proportion of fungal endocarditis in our series was 5/16 (31%) and Candida albicans (4/5) was the most common fungal pathogen. Only one patient required heart surgery because of a loose patch but all the others were treated only by medical management for cure. The hospital survival rate was 80% (4/5) and the overall long-term survival rate was 60% (3/5) with only one death directly related to fungal infection.
Keywords AdolescentAmphotericin B/therapeutic useAntifungal Agents/therapeutic useChildChild, PreschoolEndocarditis/diagnosis/drug therapy/epidemiology/microbiologyFemaleFungemia/complicationsHeart Defects, Congenital/surgeryHumansMalePostoperative Complications/epidemiology/microbiologyRetrospective StudiesSwitzerland/epidemiologyTreatment Outcome
PMID: 10206122
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Research group L'hypertension pulmonaire (pédiatrie) (228)
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ASPESBERRO, François Pierre et al. Fungal endocarditis in critically ill children. In: European Journal of Pediatrics, 1999, vol. 158, n° 4, p. 275-80. doi: 10.1007/s004310051071 https://archive-ouverte.unige.ch/unige:74301

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Deposited on : 2015-07-27

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