Scientific article
English

Fungal endocarditis in critically ill children

Published inEuropean journal of pediatrics, vol. 158, no. 4, p. 275-280
Publication date1999
Abstract

All cases of infective endocarditis occurring from January 1990 to December 1996 at our institution were reviewed, with a special focus on fungal endocarditis. Five critically ill children with fungal endocarditis and eleven children with bacterial endocarditis were recorded. The proportion of fungal endocarditis in our series was 5/16 (31%) and Candida albicans (4/5) was the most common fungal pathogen. Only one patient required heart surgery because of a loose patch but all the others were treated only by medical management for cure. The hospital survival rate was 80% (4/5) and the overall long-term survival rate was 60% (3/5) with only one death directly related to fungal infection.

Keywords
  • Adolescent
  • Amphotericin B/therapeutic use
  • Antifungal Agents/therapeutic use
  • Child
  • Child, Preschool
  • Endocarditis/diagnosis/drug therapy/epidemiology/microbiology
  • Female
  • Fungemia/complications
  • Heart Defects, Congenital/surgery
  • Humans
  • Male
  • Postoperative Complications/epidemiology/microbiology
  • Retrospective Studies
  • Switzerland/epidemiology
  • Treatment Outcome
Citation (ISO format)
ASPESBERRO, François Pierre et al. Fungal endocarditis in critically ill children. In: European journal of pediatrics, 1999, vol. 158, n° 4, p. 275–280. doi: 10.1007/s004310051071
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Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0340-6199
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