Access to enantioenriched 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter by Pd-catalyzed asymmetric intermolecular Heck reaction

Borrajo Calleja, Gustavo; Bizet, Vincent; Buergi, Thomas; Mazet, Clement

doi:10.1039/C5SC01460C

Scientific article

English

Access to enantioenriched 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter by Pd-catalyzed asymmetric intermolecular Heck reaction

ContributorsBorrajo Calleja, Gustavo; Bizet, Vincent; Buergi, Thomas; Mazet, Clement

Published inChemical science, vol. 6, no. 8, p. 4807-4811

Publication date2015

Abstract

A palladium-catalyzed intermolecular asymmetric Heck reaction with dihydrofurans with a trisubstituted double bond is reported. The use of two different chiral ligands provides access to valuable 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter with high levels of regio- and enantiocontrol.

Affiliation entities

Research groups

Groupe Mazet

Citation (ISO format)

BORRAJO CALLEJA, Gustavo et al. Access to enantioenriched 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter by Pd-catalyzed asymmetric intermolecular Heck reaction. In: Chemical science, 2015, vol. 6, n° 8, p. 4807–4811. doi: 10.1039/C5SC01460C

Article (Published version)

Identifiers

PID : unige:74172
DOI : 10.1039/C5SC01460C

Additional URL for this publicationhttp://xlink.rsc.org/?DOI=C5SC01460C

Journal ISSN2041-6520

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Creation15/07/2015 17:09:00

First validation15/07/2015 17:09:00

Update time13/10/2025 21:20:22

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Access to enantioenriched 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter by Pd-catalyzed asymmetric intermolecular Heck reaction

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