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Title

Advanced fibrosis: Correlation between pharmacokinetic parameters at dynamic gadoxetate-enhanced MR imaging and hepatocyte organic anion transporter expression in rat liver

Authors
Lagadec, Matthieu
Doblas, Sabrina
Giraudeau, Céline
Lambert, Simon A
Fasseu, Magali
Paradis, Valérie
Moreau, Richard
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Published in Radiology. 2015, vol. 274, no. 2, p. 379-86
Abstract To compare the value of enhancement and pharmacokinetic parameters measured at dynamic gadoxetate-enhanced magnetic resonance (MR) imaging in determining hepatic organic anion transporter expression in control rats and rats with advanced liver fibrosis.
Keywords AnimalsContrast Media/pharmacokineticsGadolinium DTPA/diagnostic use/pharmacokineticsHepatocytes/metabolismLiver Cirrhosis/diagnosis/metabolismMagnetic Resonance ImagingMultidrug Resistance-Associated ProteinsOrganic Anion Transporters/biosynthesisRatsRats, WistarSeverity of Illness Index
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PMID: 25289480
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Article (Published version) (657 Kb) - document accessible for UNIGE members only Limited access to UNIGE
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Research group Pharmacologie et imagerie du foie (664)
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LAGADEC, Matthieu et al. Advanced fibrosis: Correlation between pharmacokinetic parameters at dynamic gadoxetate-enhanced MR imaging and hepatocyte organic anion transporter expression in rat liver. In: Radiology, 2015, vol. 274, n° 2, p. 379-86. https://archive-ouverte.unige.ch/unige:73853

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Deposited on : 2015-07-02

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