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Title

Efficacy of sugammadex for the reversal of moderate and deep rocuronium-induced neuromuscular block in patients pretreated with intravenous magnesium: a randomized controlled trial
Authors
Czarnetzki, Christoph
Tassonyi, Edomer
Lysakowski, Christopher
Elia, Nadia
Tramer, Martin
Published in Anesthesiology. 2014, vol. 121, no. 1, p. 59-67
Abstract Magnesium enhances the effect of rocuronium. Sugammadex reverses rocuronium-induced neuromuscular block. The authors investigated whether magnesium decreased the efficacy of sugammadex for the reversal of rocuronium-induced neuromuscular block.
Keywords Adolescent — Adult — Androstanols/adverse effects/antagonists & inhibitors — Anesthesia Recovery Period — Double-Blind Method — Endpoint Determination — Female — Humans — Injections, Intravenous — Magnesium Sulfate/administration & dosage/adverse effects/pharmacology — Male — Middle Aged — Monitoring, Intraoperative — Neuromuscular Blockade/adverse effects — Neuromuscular Nondepolarizing Agents/adverse effects/antagonists & inhibitors — Preanesthetic Medication — Young Adult — Gamma-Cyclodextrins/adverse effects/pharmacology
Identifiers
PMID: 24608361
Full text
Article (Published version) (436 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences
Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de santé globale
Research group La Médecine Périopératoire et l'anesthésie (70)
Citation
(ISO format) 		CZARNETZKI, Christoph et al. Efficacy of sugammadex for the reversal of moderate and deep rocuronium-induced neuromuscular block in patients pretreated with intravenous magnesium: a randomized controlled trial. In: Anesthesiology, 2014, vol. 121, n° 1, p. 59-67. doi: 10.1097/ALN.0000000000000204 https://archive-ouverte.unige.ch/unige:73850

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Deposited on : 2015-07-02

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