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Does hepatocyte transplantation in a chemically induced acute hepatic failure make sense? |
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Published in | European Journal of Pediatric Surgery. 1998, vol. 8, no. 4, p. 224-9 | |
Abstract | Acute hepatic insufficiency (AHF) is one of the major challenges of intensive care medicine. Liver transplantation is the current solution to unsuccessful medical management. Owing to the lack of organ donors, other methods such as hepatocyte transplantation (HcTX) and bioartificial livers need to be explored. The aim of our experimental study is to evaluate the effect of hepatocyte transplantation on the survival in AHF animals intoxicated with D-Galactosamine (D-Gal). | |
Keywords | Animals — Cell Transplantation — Galactosamine/toxicity — Liver/cytology — Liver Failure, Acute/chemically induced/mortality/therapy — Male — Rats — Rats, Wistar — Spleen — Time Factors — Transplantation, Heterotopic | |
Identifiers | PMID: 9783146 | |
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Research groups | Chirurgie viscérale (104) Chirurgie viscérale (HUG) | |
Citation (ISO format) | BIRRAUX, Jacques Maurice et al. Does hepatocyte transplantation in a chemically induced acute hepatic failure make sense?. In: European Journal of Pediatric Surgery, 1998, vol. 8, n° 4, p. 224-9. doi: 10.1055/s-2008-1071159 https://archive-ouverte.unige.ch/unige:73815 |