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Title

Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement

Authors
Schoels, Monika M
van der Heijde, Désirée
Breedveld, Ferdinand C
Burmester, Gerd R
Dougados, Maxime
Emery, Paul
Ferraccioli, Gianfranco
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Published in Annals of the Rheumatic Diseases. 2013, vol. 72, no. 4, p. 583-9
Abstract Suppression of the immunoinflammatory cascade by targeting interleukin 6 (IL-6) mediated effects constitutes a therapeutic option for chronic inflammatory diseases. Tocilizumab is the only IL-6 inhibitor (IL-6i) licensed for rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), but also other agents targeting either IL-6 or its receptor are investigated in various indications.
Keywords Antibodies, Monoclonal, Humanized/therapeutic useAntirheumatic Agents/therapeutic useArthritis, Juvenile/drug therapy/immunologyArthritis, Rheumatoid/drug therapy/immunologyConsensusHumansInterleukin-6/antagonists & inhibitors/immunologySpondylitis, Ankylosing/drug therapy/immunology
Identifiers
PMID: 23144446
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Article (Published version) (314 Kb) - public document Free access
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Research group Mécanisme de l'inflammation articulaire (44)
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(ISO format)
SCHOELS, Monika M et al. Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement. In: Annals of the Rheumatic Diseases, 2013, vol. 72, n° 4, p. 583-9. https://archive-ouverte.unige.ch/unige:73677

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Deposited on : 2015-06-25

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