Optical quantum systems are ideal for testing quantum mechanical laws, but they also find many uses into possible applications to our everyday life related to quantum information science, such as quantum key distribution (QKD) or, in general, quantum communication. Nonlinear and quantum optics and their applications both to quantum communication and to tests of fundamental physics are described in this Thesis. In particular, we have developed and characterised heralded single photon sources at telecommunication wavelengths (1550 nm), based on nonlinear interactions of the second order between electric fields in dielectric materials. This is the starting point for the preparation of single photon entangled states, that we used as a resource for heralded amplification of photonic qubits, with a direct application in Device Independent Quantum Key Distribution (DIQKD) protocols, but also for testing fundamental questions in quantum physics, demonstrating the presence of entanglement in a state that counts a macroscopic number of particles, 500 photons.