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Title

Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease

Authors
Morris, K
Petros, A
Adatia, I
Bohn, D
Published in Critical Care Medicine. 2000, vol. 28, no. 8, p. 2974-8
Abstract Pulmonary hypertension is associated with congenital heart lesions with increased pulmonary blood flow. Acute increases in pulmonary vascular resistance (PVR) occur in the postoperative period after repair of these defects. These increases in PVR can be ablated by inducing an alkalosis with hyperventilation (HV) or bicarbonate therapy. Studies have shown that these patients also respond to inhaled nitric oxide (iNO), but uncertainty exists over the relative merits and undesirable effects of HV and iNO.
Keywords Administration, InhalationAdolescentAlkalosisChild, PreschoolCross-Over StudiesHeart Defects, Congenital/surgeryHumansHypertension, Pulmonary/physiopathology/therapyHyperventilationInfantNitric Oxide/administration & dosagePostoperative Complications/therapyProspective Studies
Identifiers
PMID: 10966281
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Article (Published version) (71 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group L'hypertension pulmonaire (pédiatrie) (228)
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(ISO format)
MORRIS, K et al. Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease. In: Critical Care Medicine, 2000, vol. 28, n° 8, p. 2974-8. https://archive-ouverte.unige.ch/unige:73173

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Deposited on : 2015-06-10

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