en
Scientific article
English

Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease

Published inCritical care medicine, vol. 28, no. 8, p. 2974-2978
Publication date2000
Abstract

Pulmonary hypertension is associated with congenital heart lesions with increased pulmonary blood flow. Acute increases in pulmonary vascular resistance (PVR) occur in the postoperative period after repair of these defects. These increases in PVR can be ablated by inducing an alkalosis with hyperventilation (HV) or bicarbonate therapy. Studies have shown that these patients also respond to inhaled nitric oxide (iNO), but uncertainty exists over the relative merits and undesirable effects of HV and iNO.

Keywords
  • Administration, Inhalation
  • Adolescent
  • Alkalosis
  • Child, Preschool
  • Cross-Over Studies
  • Heart Defects, Congenital/surgery
  • Humans
  • Hypertension, Pulmonary/physiopathology/therapy
  • Hyperventilation
  • Infant
  • Nitric Oxide/administration & dosage
  • Postoperative Complications/therapy
  • Prospective Studies
Citation (ISO format)
MORRIS, K et al. Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease. In: Critical care medicine, 2000, vol. 28, n° 8, p. 2974–2978.
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Article (Published version)
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Identifiers
ISSN of the journal0090-3493
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