• Home
  1. Home
  2. ATM promoter analysis in childhood lymphoid malignancies: a brief communication
Scientific article
English

ATM promoter analysis in childhood lymphoid malignancies: a brief communication

ContributorsGumy Pause, Fabienneorcid; Wacker, Pierre; Maillet, Philippe; Betts, David R; Sappino, Pascal
Published inLeukemia research, vol. 30, no. 3, p. 335-337
Publication date2006
Abstract

ATM promoter hypermethylation has been recently reported in adult carcinomas, but no information is available concerning the methylation status of ATM gene promoter in childhood B-precursor acute lymphoblastic leukaemia (ALL). Furthermore, involvement of somatic ATM promoter mutations in cancer is not known. We report a complete ATM gene promoter analysis in 74 childhood lymphoid malignancies.

Keywords
  • Adult
  • Ataxia Telangiectasia Mutated Proteins
  • Burkitt Lymphoma/genetics
  • Carcinoma/genetics
  • Cell Cycle Proteins/genetics
  • Child
  • Child, Preschool
  • DNA Methylation
  • DNA-Binding Proteins/genetics
  • Female
  • Humans
  • Male
  • Point Mutation
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics
  • Promoter Regions, Genetic/genetics
  • Protein-Serine-Threonine Kinases/genetics
  • Sequence Analysis, DNA
  • Tumor Suppressor Proteins/genetics
Affiliation entities
Research groups
Citation (ISO format)
GUMY PAUSE, Fabienne et al. ATM promoter analysis in childhood lymphoid malignancies: a brief communication. In: Leukemia research, 2006, vol. 30, n° 3, p. 335–337. doi: 10.1016/j.leukres.2005.07.012
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0145-2126
466views
1downloads

Technical informations

Creation29/01/2015 14:25:00
First validation29/01/2015 14:25:00
Update14/03/2023 23:21:54
Status update14/03/2023 23:21:53
Last indexation31/10/2024 00:27:00
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack