Lung volume recruitment after surfactant administration modifies spatial distribution of ventilation

Frerichs, Inéz; Dargaville, Peter A; van Genderingen, Huibert; Morel, Denis; Rimensberger, Peter

doi:10.1164/rccm.200512-1942OC

Scientific article

English

Lung volume recruitment after surfactant administration modifies spatial distribution of ventilation

ContributorsFrerichs, Inéz; Dargaville, Peter A; van Genderingen, Huibert; Morel, Denis; Rimensberger, Peter

Published inAmerican journal of respiratory and critical care medicine, vol. 174, no. 7, p. 772-779

Publication date2006

Abstract

Although surfactant replacement therapy is an established treatment in infant respiratory distress syndrome, the optimum strategy for ventilatory management before, during, and after surfactant instillation remains to be elucidated.

Keywords

Animals
Animals, Newborn
Blood Gas Analysis
Disease Models, Animal
Electric Impedance
Instillation, Drug
Lung/drug effects/physiology
Pulmonary Surfactants/pharmacology
Respiration, Artificial
Respiratory Mechanics/drug effects/physiology
Swine

Affiliation

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research group

Maladies pulmonaires aigues et pathologies cardiaques congénitales (697)

Citation (ISO format)

FRERICHS, Inéz et al. Lung volume recruitment after surfactant administration modifies spatial distribution of ventilation. In: American journal of respiratory and critical care medicine, 2006, vol. 174, n° 7, p. 772–779. doi: 10.1164/rccm.200512-1942OC

Article (Published version)

Identifiers

PID : unige:73112
DOI : 10.1164/rccm.200512-1942OC
PMID : 16840739

ISSN of the journal1073-449X

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Lung volume recruitment after surfactant administration modifies spatial distribution of ventilation

Although surfactant replacement therapy is an established treatment in infant respiratory distress syndrome, the optimum strategy for ventilatory management before, during, and after surfactant instillation remains to be elucidated.

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