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Lung recruitment and lung volume maintenance: a strategy for improving oxygenation and preventing lung injury during both conventional mechanical ventilation and high-frequency oscillation |
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Published in | Intensive Care Medicine. 2000, vol. 26, no. 6, p. 745-55 | |
Abstract | To determine whether using a small tidal volume (5 ml/kg) ventilation following sustained inflation with positive endexpiratory pressure (PEEP) set above the critical closing pressure (CCP) allows oxygenation equally well and induces as little lung damage as high-frequency oscillation following sustained inflation with a continuous distending pressure (CDP) slightly above the CCP of the lung. | |
Keywords | Animals — High-Frequency Ventilation/adverse effects/methods — Intermittent Positive-Pressure Ventilation/adverse effects/methods — Lung/pathology — Peroxidase/metabolism — Pulmonary Gas Exchange — Rabbits — Random Allocation — Respiratory Distress Syndrome, Adult/physiopathology/prevention & control — Respiratory Mechanics — Tidal Volume | |
Identifiers | PMID: 10945393 | |
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Research group | Maladies pulmonaires aigues et pathologies cardiaques congénitales (697) | |
Citation (ISO format) | RIMENSBERGER, Peter et al. Lung recruitment and lung volume maintenance: a strategy for improving oxygenation and preventing lung injury during both conventional mechanical ventilation and high-frequency oscillation. In: Intensive Care Medicine, 2000, vol. 26, n° 6, p. 745-55. doi: 10.1007/s001340051242 https://archive-ouverte.unige.ch/unige:73097 |