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Title

Peripheral blood progenitor cell mobilization and leukapheresis in pigs

Authors
Nash, K
Chang, Q
Watts, A
Treter, S
Oravec, G
Ferrara, V
Basker, M
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Published in Laboratory Animal Science. 1999, vol. 49, no. 6, p. 645-9
Abstract The pig is being investigated as an organ donor for humans. Induction of immunologic tolerance to pig tissues in primates would overcome the major immunologic barriers to xenotransplantation. A proven method of inducing tolerance to allografts is by the induction of mixed hematopoietic chimerism by bone marrow transplantation. We are therefore investigating induction of mixed hematopoietic chimerism in the pig-to-baboon model.
Keywords AnimalsFemaleGranulocyte Colony-Stimulating Factor/pharmacologyHematopoiesis/drug effectsHematopoietic Stem Cell Mobilization/methods/veterinaryHematopoietic Stem Cells/drug effectsHumansInterleukin-3/pharmacologyLeukapheresis/methods/veterinaryLeukocyte Count/drug effects/veterinaryLeukocytes/drug effectsMaleStem Cell Factor/pharmacologySwineSwine, Miniature/physiology
Identifiers
PMID: 10638501
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Research group Cultures cellulaires et transplantations (519)
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NASH, K et al. Peripheral blood progenitor cell mobilization and leukapheresis in pigs. In: Laboratory Animal Science, 1999, vol. 49, n° 6, p. 645-9. https://archive-ouverte.unige.ch/unige:72967

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Deposited on : 2015-06-03

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