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Utilité du dosage plasmatique de la procalcitonine chez l'adulte et chez l'enfant

Published in Revue médicale suisse. 2005, vol. 1, no. 13, p. 872-4,877
Abstract In febrile children and adults, it is frequently difficult, based on the sole clinical examination, to differentiate a bacterial illness from systemic inflammatory syndromes or severe viral infections. However, the positive and rapid diagnosis of a severe bacterial infection or a sepsis is essential to initiate lifesaving therapies. Among the numerous infectious biomarkers that have recently been investigated, procalcitonin has the best diagnostic yield. Plasma levels below 0.5 microg/l usually rule out a severe bacterial disease, whereas values above 2 microg/l are strongly indicative of a bacterial sepsis. The usefulness and the limitations of the measurement of procalcitonin as a diagnostic and a prognostic tool during severe bacterial infections are discussed in this paper.
Keywords AdultBiological Markers/bloodCalcitonin/bloodChildDiagnosis, DifferentialFever/etiologyGlycoproteinsHumansInflammation/complicationsProtein Precursors/bloodSepsis/complications/diagnosisSyndromeVirus Diseases/complications
PMID: 15895929
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Other version: http://www.revmed.ch/rms/2005/RMS-13/30261
Research group Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
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GERVAIX, Alain, PUGIN, Jérôme. Utilité du dosage plasmatique de la procalcitonine chez l'adulte et chez l'enfant. In: Revue médicale suisse, 2005, vol. 1, n° 13, p. 872-4,877. https://archive-ouverte.unige.ch/unige:72870

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Deposited on : 2015-05-28

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