The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth

Genevaux, P.; Schwager, Françoise; Georgopoulos, C.; Kelley, William

doi:10.1128/JB.183.19.5747-5750.2001

Scientific article

English

The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth

ContributorsGenevaux, P.; Schwager, Françoise; Georgopoulos, C.; Kelley, William

Published inJournal of bacteriology, vol. 183, no. 19, p. 5747-5750

Publication date2001

Abstract

The DnaK chaperone of Escherichia coli is known to interact with the J domains of DnaJ, CbpA, and DjlA. By constructing multiple mutants, we found that the djlA gene was essential for bacterial growth above 37 degrees C in the absence of dnaJ. This essentiality depended upon the J domain of DjlA but not upon the normal membrane location of DjlA.

Keywords

DNA-Binding Proteins/genetics/metabolism
Escherichia coli/genetics/ growth & development/metabolism
Escherichia coli Proteins
HSP40 Heat-Shock Proteins
Heat-Shock Proteins/ genetics/ metabolism
Hot Temperature
Mutation

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Citation (ISO format)

GENEVAUX, P. et al. The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth. In: Journal of bacteriology, 2001, vol. 183, n° 19, p. 5747–5750. doi: 10.1128/JB.183.19.5747-5750.2001

Article

Identifiers

PID : unige:7267
DOI : 10.1128/JB.183.19.5747-5750.2001
PMID : 11544239

Additional URL for this publicationhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC95468/pdf/jb005747.pdf

Journal ISSN0021-9193

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The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth

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